“Does CBD help with pain?” has become a popular question in Google search, as many are looking for a better, natural alternative to combat discomfort. The opioid epidemic has only gotten worse since the 1990s. Nearly 500,000 have died from a prescription overdose and more than 2 million Americans abuse opioids.

For those seeking a replacement for some of these medications, hemp-infused products may be considered. While we still don’t have all the answers about CBD’s therapeutic properties, we do have some idea of how it can help manage different types of pain.

A woman holding a glass of water in one hand and a pill in the other.  The opioid epidemic has caused many to ask, "Does CBD help with pain?"

Can CBD help manage different kinds of pain?

In order to understand how CBD affects pain in the body, we need to look at the endocannabinoid system (ECS).

The ECS is made up of enzymes, receptors, and endocannabinoids that help regulate various functions and processes throughout our body. This includes sleep, mood, appetite, and pain sensation. Scientists have limited studies describing all the ECS is responsible for, but we do know it is vital in maintaining homeostasis

It’s already been discovered that CBD presents anti-inflammatory and antioxidant properties. Another group of researchers reviewed every study from 1975 to 2018 on the effects of CBD for chronic pain caused by neurological disorders like multiple sclerosis and fibromyalgia. It was concluded that CBD not only helped with pain management, but patients exhibited little to no negative side effects.

What remains somewhat of a mystery is how CBD interacts with the ECS. CBD has a low binding affinity with the CB1 and CB2 receptors, but it can interact with them as an antagonist, meaning it suppresses the receptor’s ability to activate qualities of other cannabinoids. Researchers believe this is how CBD weakens THC’s psychotropic effects.

Hemp plants in a field at dusk.

Studies on CBD for pain management 

Sadly, years of prohibition and stigma have put the U.S government far behind in its understanding of the efficacy of cannabis and CBD. Even now, companies in the industry are still treading murky waters regarding how their products can be marketed to the public. The US. Food and Drug Administration (FDA) has not been shy about calling out multiple businesses in the past who claim CBD can treat conditions like Alzheimer’s and cancer. 

“Selling unapproved products with unsubstantiated therapeutic claims — such as claims that CBD products can treat serious diseases and conditions — can put patients and consumers at risk by leading them to put off important medical care,” stated Acting FDA Commissioner Ned Sharpless, M.D.

However, regardless of government oversight, people have been making testimonials on the benefits of CBD for years. Many patients who consume or apply CBD for pain management are doing so for various medical conditions. And thanks to the efforts made by independent researchers, several accredited studies exist suggesting how CBD does, in fact, provide the therapeutic benefits people have raved about.

trupura CBD Hemp Oil Tincture on a white background.  When asked, "Does CBD help with pain?", some users of this product reported, "yes."

Here is what their results have discovered so far:

  • A 2018 study showed CBD could help improve mobility in patients with Multiple Sclerosis (MS). An oral spray developed by GW Pharmaceuticals called Sativex (known as Nabiximols in the U.S.) is allowed in numerous countries for MS patients as a treatment for muscle spasticity. It’s also undergoing a clinical program in the U.S. to receive FDA approval. 
  • CBD has been looked at as a possible treatment option for various epilepsy syndromes for many years. Other studies reveal CBD may even enhance the effects of clobazam, a medicine often used by people with epilepsy. Currently, Epidiolex is the only FDA-approved cannabis medicine for treating seizures caused by Lennox-Gastaut syndrome and Dravet syndrome. 
  • Some researchers think the anti-inflammatory properties found in CBD could be beneficial for people suffering from arthritis. A study done on rats in 2016 saw a reduction in the inflammation and pain affecting the joints. 
  • The FDA has two different cannabis medications, nabilone and dronabinol, that are approved for treating nausea and vomiting caused by chemotherapy. However, these are not made of CBD alone. Another study performed by researchers at Queen Mary University in London and Curtin University in Australia found that mice with pancreatic cancer survived almost three times longer when CBD was paired alongside their chemotherapy treatments.
young couple runner running on running road in city park

CBD products: What works best for which type of pain?

The CBD market is overflowing with incredible products that help patients and consumers manage all kinds of pain. Whether it’s for mild soreness or to relieve pain created by severe neurological diseases, there’s definitely something for everyone. 


Lotions, creams, and salves are ideal for targeting localized pain and inflammation. Our Extra Strength Salve offers a cooling and relieving sensation that soothes cramps, sore muscles, and swelling. For some people, the effects will last all day, but others may need to reapply the product when needed. CBD topicals are also beneficial for skincare and can help calm flare-ups and irritation from conditions like eczema and psoriasis. 

Oils and tinctures

CBD tinctures and oils are a popular choice for regular and first-time CBD users. They can be added to almost anything and the full-body effects can last anywhere from a few hours to all day depending on the dosage. Many people put the tincture in drinks or food, while others simply place it under the tongue. 


Gummies and candies and chocolate, oh my! CBD edibles have overtaken dispensaries across the country and online. There’s no shortage of delicious flavors and they’re easy to consume without anyone being the wiser. Our trupuraCBD wild strawberry, green apple, and sweet watermelon gummies are definitely crowd-pleasers for all-day relief! Most find that 25mgs is more than enough to leave them feeling relaxed and euphoric. Check out our blog on CBD dosing for a quick prep course on how much you really need to get the job done!

A container of trupura CBD Bath Salts resting on a white and blue striped towel next to a seashell and bar of soap.

Get your CBD products from a brand you can trust

We’ve worked tirelessly since 2010 to help our customers live a fulfilling life free from aches and pains. Our CBD products are made from Colorado state-certified hemp and are always third-party tested. Check out our store locator to see if trupuraCBD is available at your local dispensary.

If you’d like to learn more about how CBD could help manage your symptoms, speak to a certified cannabis nurse at Leaf 411.

Leave a Reply

This site uses Akismet to reduce spam. Learn how your comment data is processed.